After renal transplantation, a large percentage of patients lose bone. This loss of bone results from a combination of factors that include pre-existing renal osteodystrophy, immunosuppressive therapy, and the effects of chronically reduced renal function after transplantation. Many studies have found that the type of bone disease that pre dominates in the post transplantation world is Low turnover disease. Low bone volume and low bone turnover has been associated with cardiovascular calcifications. Do we use less Vitamin D in these patients, more of cinacalcet, the data is scant? This review might help answer few questions and stem more for further research.
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