A recent study in AJT March 2010 issue evaluated what happens to patients after they get a kidney transplant in terms of their nephrogenic systemic fibrosis disease. They studied 17 patients retrospectively.
Nine of 11 transplanted patients had NSF pre transplant and 2 had post transplant DGF and then NSF.
6 dialysis patients with NSF were also studied. They followed these patients for 35 months for post transplant patients and 9 months for dialysis patients. Baseline GFR for transplant patients were 42ml.min.
NSF only improved in 55% of transplant patients and 50% of non transplanted patients. Of the 6 patients of the 11 total transplanted patients, 4 had partial remission and 2 had complete remission of NSF.
It seems that they summarize that transplant or no transplant, 50% had some remission of NSF. So it doesn't seem that transplantation changed outcomes for their NSF.
This is important as this is the largest study of NSF in transplant patients I found so far. Hopefully a more prospective study might be more helpful. In general, i think we are going to see less and less of this disease as we are avoiding gadolinium based MRIs in many of our CKD and post transplant CKD patients.
Monday, March 22, 2010
Subscribe to:
Post Comments (Atom)
All Posts
-
▼
2010
(461)
-
▼
March
(37)
- CLINICAL CASE 9
- The Online Transplant Center: Post transplant MPGN
- Post transplant MPGN
- TOPIC DISCUSSION: PCO2, which one is better?
- Image Quiz- Answers
- CONSULT ROUNDS: METHANOL and the EYE?
- CONSULT ROUNDS: ACID BASE
- JOURNAL CLUB: Kidney allograft nephrectomy can imp...
- TOPIC DISCUSSION: Nutrition
- TOPIC DISCUSSION: Drugs and Cyclosporine
- IN THE NEWS- NSF and Kidney Transplantation
- Bowel Transplantations, not enough!
- Horseshoe Kidney
- The Online Transplant Center: New Agents for renal...
- CLINICAL CASE 8
- History of Nephrology: The first randomised contro...
- Common Sense vs. Evidence-based Medicine
- TOPIC DISCUSSION: DIFFERENT TYPES OF PROTEINURIA
- New Agents for renal transplantation
- TOPIC DISCUSSION: Renal Artery Stenosis
- TOPIC DISCUSSION: THE WWW and the NEPHROLOGIST
- IN THE NEWS- Hyperkalemia treatment in trouble
- IN THE NEWS ---> ACUTE KIDNEY INJURY
- CONSULT ROUNDS: SIADH and Escitalopram ( lexapro)
- CONSULT ROUNDS: Clinical dilemma in Nephrogenic Di...
- CONSULT ROUNDS: Metformin toxicity, Lactic Acidosi...
- CLINICAL CASE 7
- IN THE NEWS- HgA1C for Diabetes Diagnosis. How abo...
- KIDNEY DONORS have Good Long term survival
- TOPIC DISCUSSION: VEGF Nephropathology
- TOPIC DISCUSSION: Post Transplant Collapsing FSGS,...
- Post Transplant Collapsing FSGS: Is it really all ...
- CLINICAL CASE 6
- Topic Discussion: OUCH!! Should Anesthesia Hurt??
- TOPIC DISCUSSION: Alcohol Poisonings, gaps and osm...
- Belatacept approved by FDA
- Protocol Biopsies in Renal Allograft Recipients
-
▼
March
(37)
No comments:
Post a Comment