Thursday, June 2, 2011

TOPIC DISCUSSION: Hemoperfusion vs Hemodialysis for poisons?

Hemoperfusion is the passage of anticoagulated blood through a column containing activated charcoal or resins that helps remove lipid bound and water bound drugs. Drug removal using this form might be superior to hemodialysis.  If the drug is water soluble, and has significant metablic complications  and rebound properties, hemodialysis might be better. If the drug is lipid soluble like barbiturates, hypnotics, sedatives and digitalis might work better with hemoperfusion.

Ref:
http://www.ncbi.nlm.nih.gov/pubmed/21531322
http://www.ncbi.nlm.nih.gov/pubmed/20692080

1 comment:

  1. Is it possible to remove a long chain virus directly from blood? Some work has been performed on aids patients with mixed results. How about removal of Ebola directly from blood with hemoperfusion? Darell Engelhaupt

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