What degree of Class IV lupus nephritis presents with just hematuria?
What degree of Class I lupus nephritis presents with just hematuria?
Take a look at this data from a recent paper in 2009 by Seshan et al.
Of 541 patients studied for classification of lupus nephritis,
40% of Class I, 19% of Class II, 22% of Class III, 4% of Class IV and 6% of Class V presented with asymptomatic hematuria.
40% of Class I, 42% of Class II, 25% of Class III, 7% of Class IV and 13% of Class V present with asymptomatic proteinuria
20% of Class I, 15% of Class II, 17% of Class III, 40% class IV and 65% of Class V presented with Nephrotic Syndrome.
20% of Class II, 34% of Class III, 27% of Class IV and 7% of Class V presented with Nephritic Syndrome
4% of Class II, 2% of Class III, 18% of Class IV and 2% of Class V presented with Acute renal failure
4% of Class IV and 8% of Class V had presented with Chronic renal injury.
So in summary: Lupus can present on kidney biopsy much more differently than clinically. Look at the wide spectrum of just hematuria and proteinuria.
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