Complement Component Quiz Answers

Question:

Match the following complement components with their function in the complement cascade

C5a	Membrane attack complex
DAF	Initiates the alternative complement pathway
C5b-9	Initiates the classical complement pathway
Factor H	Byproduct of the classical complement pathway
C5	Potent inflammatory mediator
C1q	Membrane bound complement regulatory protein
C4d	Blockade of this complement component is the treatment for PNF
C3b	Deficiency results in atypical HUS

Answers:

C5a – Potent inflammatory mediator

DAF (decay accelerating factor) – membrane bound complement regulatory protein

C5b-9 – membrane attack complex (MAC)

Factor H – Deficiency results in atypical HUS (hemolytic uremic syndrome)

C5 - Blockade of this complement component is the treatment for PNF (paroxysmal nocturnal hematuria)

C1q – Initiates the classical complement pathway

C4d - Byproduct of the classical complement pathway

C3b - Initiates the alternative complement pathway

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Vinay Nair