As the Antibodies to phospholipase A2 receptor story goes for Membranous GN, the soluble urokinase for FSGS , there is emerging story about ANGPTL4 overproduction in podocytes leading to minimal change disease. This abnormal overproduction of this protein leads to podocyte foot process effacement nicely shown in some recent work by Chugh et al.
Two recent commentaries by clinical Pathologists take a fresh look at this topic.
An original post by us highlighted the original publication in 2010.
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