The strongest predictors of cancer as a cause of Membranous GN are:
1. Smoking
2. Advanced Age
3. Leukocytic infiltration of the glomeruli( eight leukocytes per glomerulus has a sensitivity of 75% and specificity of 92%)
For an interesting case discussion regarding this, visit
CJASN's attending Rounds on Nephrotic Syndrome in an older patient
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