Clinical Case 74: Answers and Summary

True or False: The standard measurement of anion gap will miss lactic acidosis if the lactate level is <10

True	24 (72%)
False	9 (27%)

Anion gap will miss lactic acidosis if lactate <10.
misses 50% lactate 5-10,
misses 80% if Lactate 3-5

Interesting, many cases would be missed if we just relied on the anion gap. Interestingly, such an old study done in 1990s: probably worth re looking at this phenomenon and why?