Here is a list of common anti hypertensive agents used in ESRD and clearance via HD. In general, ACEI are removed in variable amounts, ARBs and aldo antagonists are not. Beta blockers are variable. CCB are variable but in general not that removed.
Class
|
%Removal with
hemodialysis |
||
Angiotensin converting enzyme inhibitors
|
|||
Captopril
|
Yes
|
||
Benazepril
|
20–50%
|
||
Enalapril
|
35%
|
||
Fosinopril
|
<10%
|
||
Lisinopril
|
50%
|
||
Quinapril
Ramipril |
<10%( limited data)
<30% |
||
Angiotensin receptor blockers
|
|||
Losartan
|
None
|
||
Candesartan
|
None
|
||
Eprosartan
|
None
|
||
Telmisartan
|
None
|
||
Valsartan
|
None
|
||
Irbesartan
|
None
|
||
Aldosterone antagonists
|
|||
Spironolactonea
|
None
|
||
Eplerenoneb
|
None
|
||
Renin inhibitor
|
|||
Aliskiren
|
?
|
||
β-Blockers and combined α- and β-blockers
|
|||
Atenolol
|
75%
|
||
Metoprolol
|
High
|
||
Metoprolol XL
|
High
|
||
Propranolol
|
<5%
|
||
Carvedilol
|
None
|
||
Carvedilol CR
|
None
|
||
Labetalol
|
<1%
|
||
Calcium channel blockers
|
|||
Amlodipine
|
None
|
||
Diltiazem
|
<30%
|
||
Nifedipine
|
Low
|
||
Nicardipine
|
?
|
||
Felodipine
|
No
|
||
Verapamil
|
Low
|
||
Alpha-adrenergic blockers
|
|||
Doxazosinc
|
None
|
||
Terazosin
|
None
|
||
Prazosin
|
?
|
||
Other
|
|||
Clonidine
|
<5%
|
||
Hydralazine
|
None
|
||
Isosorbide dinitrate
|
Yes
|
||
Minoxidil
|
Partially
|
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