A scientific statement was just issued on cardio-renal
syndrome by the AHA. This is one of the first and comprehensive summary on
cardio-nephrology. The mission of this scientific statement is to describe the epidemiology and pathogenesis of cardiorenal
syndrome in the context of the
continuously evolving nature of its clinicopathological description over the past decade. It also describes
diagnostic and therapeutic strategies
applicable to cardiorenal syndrome, summarizes cardiac-kidney interactions in special populations
such as patients with diabetes mellitus
and kidney transplant recipients, and emphasizes the role of palliative care in patients with
cardiorenal syndrome. Some of the key summaries in the large statement are
summarized in table 8 of the freely available statement. The important ones are: Distinguishing true AKI from
functional causes of fluctuations in serum creatinine
in the context of diuresis for acute decompensated heart failure is critical in ensuring delivery of goal-directed
medical therapies; Identifying the factors contributing to diuretic resistance
is a key step in optimizing
decongestion in cardio-renal syndrome(CRS); Biomarkers of cardiac and kidney
injury represent a new dimension in the diagnostic
algorithm in evaluating HF with impaired kidney function and offer prognostic value in acute and chronic
CRS; High-quality data for goal-directed medical therapy in chronic CRS with moderate to severe decline in kidney
function are lacking. In addition, a multidisciplinary approach is required for
cardiac device therapies to reduce
arrhythmia burden in patients with CHF and CKD. Palliative care is an underused
strategy in patients with the dual burden of CHF
and advanced CKD. A cardio-nephrology
multidisciplinary approach is essential in the joint management of patients with CRS with an
emphasis on core outcome measures
based on patient and physician priorities. Cross specialty educational
programs are extremely important to promote the data on this important topic
and also to increase awareness of newer technology. In addition, cross talk
within two specialties could breed important decisions to improve patient
related outcomes.
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